DIFFUSE LARGE B-CELL LYMPHOMA OF THE HEART

Diffuse large B-cell lymphoma (DLBCL) of the heart accounts for only 1% primary cardiac tumors. Histopathologic examination becomes key diagnosis and immunohistochemical evaluation non-Hodgkin (NHL) subtype determination is able to predict disease progression therapeutical modality. Case description: 70-year-old man complained shortness breath. Echocardiographic revealed mass occupied left atrium measured 5.9 x 2.9 cm inherent with interatrial septum a stem in right 4.6 2.4 cm. Intraoperative, considerable amount extracardiac was found, extension unable be determined. Thoracic surgeon decided sample without performing surgery. The histopathologic features showed round blue cell tumor resembling NHL. Immunohistochemical staining were consistent diffuse NHL, cell, high grade lymphoma, suitable DLBCL. Round positive expression LCA CD 20 lymphoma. Ki-67 70-80% proliferation index which indicates high-grade defining treatment